Products
2,4-Diamino-6-hydroxypyrimidine 2,6-Diamino-4-Hydroxyprimidine
Synonyma: 4(1H)-pyrimidinone;2,6-diamino-(8CI,9CI); -dihydropyrimidin-4-one;2,6-diamino-4(1H)-pyrimidinone;2,6-diamino-4(3H)-pyrimidinone;2,6-Diamino-4-hydroxypyrimidine; -pyrimidinol;2,6-diaminopyrimidinum-4-unum;2,6-diaminopyrimidinum-4(3H)unum;6-aminoisocytosinum;6-hydroxy-2,4-pyrimidinediamine;NSC 44914;NSC 680818;NSC9302;
Chemical Property of 2,4-Diamino-6-hydroxypyrimidine
Aspectus / Color: solidum album
Vapor Pressure: 0.00232mmHg ad 25°C
● Punctum punctum: 285-286 °C (decl.)(lit.)
● Refractivus Index: 1.7990 (aestimatio)
Fervens Point:28.5 °C at 760 mmHg
● PKA: 10.61±0.50(Praedicta)
Flash Point:128.3 °C
PSA：98.05000
Densitas: 1.84 g/cm3
LogP: 0.50900
Repono Temp.:Desiccate ad +4°C
Sensitive.:Lux Sensitiva
Solubility.:DMSO (paulo), Methanol (Pauliter)
Puritas / Quality
XCIX% * notitia rudis a amet
2-3
Safty Information
Pictogram(s);
Xi
DISCRIMEN Codes:Xi
Dictiones 36/37/38
Salus Denunciationes: 22-24/25-36-26
Utilis
● Descriptio: 2,4-Diamino-6-hydroxypyrimidinum (DAHP) est selectivum, specificum inhibitoris GTP cyclohydrolasis I, gradatim limitans pro synthesi novo pterin.In cellulis HUVEC, IC50 in inhibitionis biosynthesis BH4 est circiter 0.3 mM.DAHP adhiberi potest ad nullas productiones efficaciter angustas in pluribus cellulis speciebus.
● Usus: 2,4-Diamino-6-hydroxypyrimidine (DAHP) est selectiva, specifica inhibitor GTP cyclohydrolasis I, gradatim limitans pro synthesi novo pterin.In cellulis HUVEC, IC50 in inhibitionis biosynthesis BH4 est circiter 0.3 mM.DAHP adhiberi potest ad nullam productionem efficaciter obstruendam in pluribus speciebus cellis. [Cayman Chemical] Stat in principio cascade enzyme catalysi qui incipit ab hoc carbohydrato septem- carbo et terminatur cum amino aromatico acida phenylalanina, tyrosina et tryptophan. 2,4-Diamino-6-hydroxypyrimidinum (cas# 56-06-4) compositum utile est in synthesi organica.
2,4-Diamino-6-hydroxypyrimidine est compositum chemicum cum formula hypothetica C4H6N4O.Communiter usus est ut medium in synthesi variarum compositorum, inter medicamenta pharmaceutica et dyes. Compositum habet structuram anuli pyrimidinem duobus amino coetibus (NH2) et unum globum hydroxyli (OH) diversis atomis carbonis adnexum.Haec structura eam versatilem clausuram aedificationis facit ad synthesin moleculorum complexorum.2,4-Diamino-6-hydroxypyrimidine variis modis syntheticis, incluso reactione cyanamidis cum urea.Plures applicationes habet in industria pharmaceutica, praesertim in synthesi anticancri medicamentorum et antibioticorum. Super, 2,4-Diamino-6-hydroxypyrimidine compositio magni momenti est quae utilitatem in variis chemicis et pharmaceuticis invenit.
