2,4-Diamino-6-hydroxypyrimidine

Description:

Product nomen:2,4-Diamino-6-hydroxypyrimidine

Synonyma:TIMTEC-BB SBB004252;2,4-DIAMINOPYRIMIDIN-6-OL;2,4-DIAMINO-6-HYDROXYPYRIMIDINE;2,4-DIAMINO-6-PYRIMIDINOL;2,4-DIAMINO-6(1H)-PYRIMIDINONE; 6-DIAMINO-4-PYRIMIDINOL;2,6-DIAMINO-4-PYRIMIDINONE;2,6-DIAMINOPYRIMIDIN-4-OL

CAS;56-06-4

MF:C4H6N4O

MW:126.12

EINECS:200-254-4

Categoria:Pyrimidines;exstructiones;PYRIMIDINE;C4 ad C5;Chemica Synthesis; Heterocyclica Aedificium Cuneos; APIs & Medium; Pyridines, Pyrimidines, Purines & Pteredines;Amines Chemical;13C & 2H Sugars;Amines;Bases & Reagents; Heterocycles; & Derivationes, bc0001

Mol fasciculi:56-06-4.mol

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Hydroxypyrimidine Chemical Properties

Liquescens punctum	285-286 °C (decl.)
Ferveret	234.22°C (aestimatio aspera)
density	1.3659 (aestimatio aspera)
refractivus index	1.7990 (aestima)
repono temp.	Serva in caliginoso loco, atmosphaera Inert, locus temperatus
solubility	DMSO (paulo), Methanol (paulo)
pka	10.61±0.50 (Praedicta)
forma	Pulchra crystallina pulveris
color	Alba ad crepito
Sensitiva	lux Sensitiva
Merck	14,2981
BRN	125006
InChIKey	SWELIMKTDYHAOY-UHFFFAOYSA-N
CAS Reference	56-06-4 (CAS Reference)
NIST Chemia Reference	4(1H)-pyrimidinone, 2,6-diamino-(56-06-4)
EPA Substantia Registry System	2,6-Diamino-4(1H)-pyrimidinone (56-06-4)

Hydroxypyrimidine Product Description

2,4-Diamino-6-hydroxypyrimidine est compositum chemicum cum formula hypothetica C4H6N4O.Compositum est organicum familiae pyrimidinis pertinens.Compositum pyrimidinem structuram anuli habet, duo coetus amino (NH2) conexi cum 2-positione et 4-positione, et globus hydroxylus (OH) cum 6-positione connexus est.Chemica structura exprimi potest ut: Ammonia ||H--C--C--C--N--C--C--NH2 ||oh 2,4-Diamino-6-hydroxypyrimidine varias applicationes in pharmaceutica industria habet.Medium magni momenti est in synthesi multarum medicamentorum, in quibus medicinae antiviralis et antitumor est.Usus est etiam ad plura analoga nucleotide in pharmaceutica inquisitione adhibita.

Praeter medicamenta medicamenta, 2,4-diamino-6-hydroxypyrimidine medicamenta in agrochemicals adhibetur.Clavis est ingrediens in synthesi plantae incrementi regulatores et fungicides.Magni interest ut propriam salutem protocollo sequantur cum adhibita 2,4-diamino-6-hydroxypyrimidine.Cum inritamentum chemicum generetur, cura et adaequata instrumenta tutelae personalis tractari debet ad contactum directum vitandum.

In summa, 2,4-diamino-6-hydroxypyrimidine compositum est organicum cum applicationibus in agris pharmaceuticis et agriculturae.Eius structura chemica eam utilem facit ut medium in synthesi pharmaceuticae et incrementi regulatores plantandi.

Salus Information

Periculum Codes	Xi
Periculum Denunciationes	36/37/38
Salus Denunciationes	22-24/25-36-26
WGK Germania	3
Aleam Nota	Irritant
TSCA	Ita
HS Code*	29335995

Hydroxypyrimidine Synthesis Synthesis

Descriptio	2,4-Diamino-6-hydroxypyrimidinum (DAHP) est selectivum, specificum inhibitoris GTP cyclohydrolasi I, gradatim limitans pro synthesi novo pterin.In cellulis HUVEC, IC₅₀inhibitionis BH*₄biosynthesis est circiter 0,3 mM.DAHP adhiberi potest ad nullas productiones efficaciter angustas in pluribus cellulis speciebus.
Chemical Properties	Solidus albus
usus	2,4-Diamino-6-hydroxypyrimidinum (DAHP) est selectivum, specificum inhibitoris GTP cyclohydrolasi I, gradatim limitans pro synthesi novo pterin.In cellulis HUVEC, IC50 in inhibitionis biosynthesis BH4 est circiter 0.3 mM.DAHP adhiberi potest ut efficaciter nullum productionem impediat in pluribus cellulis speciebus.[Cayman Chemical]
usus	Stat in principio cascade enzyme-catalytici qui cum hoc carbohydrato septem-carbo incipit et cum amino amino aromatico phenylalanino, tyrosino et tryptophano terminatur.
usus	2,4-Diamino-6-hydroxypyrimidinum (cas# 56-06-4) compositum utile est in synthesi organica.
Purificationis Methodi	Recrystallises ab H2O.[Beilstein 25 III/IV 3642.]